Dr. El-Ghannam’s laboratory is dedicated to the design of novel bioactive nano-composites for applications in orthopedic and maxillofacial surgeries, tissue engineering and targeted drug delivery in soft and hard tissues. Our research interest is focused on:
Developing multifunctional drug delivery systems to treat various diseases including osteoarthritis, osteomyelitis and breast cancer.
Engineering of innovative orthopedic fixation devices using mechanically compatible bioactive ceramic.
Improving the performance of artificial joints and load bearing implants through surface modifications and coating with bioactive ceramic.
Cryopreservation of mesenchymal stem cells in porous resorbable scaffolds to provide an unlimited supply of biological bone grafts.
The work includes studies of the correlation among structure-processing and material properties, cell-material interactions, drug release kinetics, surface characterization, mechanical behavior, dissolution kinetics, molecular biology assays and animal surgeries, histopathology and radiography.